Yes, it is definitely safe to implement ShortPoint as a full-trust solution.
ShortPoint uses the SharePoint Framework (SPFx) development model which supports client-side SharePoint development and integration with SharePoint data. It is also referred to as a full trust client-side solution. By its nature, it contains full trust client-side code and can run in full trust.
At ShortPoint, we fully comply with Microsoft Office 365, SharePoint, and SAP Cloud Security principles and implementations when developing our solution. All scripts are executed within the safety of your SharePoint environment and we do not provision access to your content by any means. We also set further security features to ensure that all data and information are safe at all times.
Check out our ShortPoint Security and Protection Implementation article to learn more.